Deep sequencing reveals variations in somatic cell mosaic mutations between monozygotic twins with discordant psychiatric disease

Monozygotic (MZ) twins have been thought to be genetically identical. However, recent studies have shown discordant variants between them. We performed whole-exome sequencing (WES) in five MZ twin pairs with discordant neurodevelopmental disorders and one healthy control MZ twin to detect discordant...

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Veröffentlicht in:Hum Genome Var
Hauptverfasser: Morimoto, Yoshiro, Ono, Shinji, Imamura, Akira, Okazaki, Yuji, Kinoshita, Akira, Mishima, Hiroyuki, Nakane, Hideyuki, Ozawa, Hiroki, Yoshiura, Koh-ichiro, Kurotaki, Naohiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529667/
https://ncbi.nlm.nih.gov/pubmed/28765789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hgv.2017.32
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