Deep sequencing reveals variations in somatic cell mosaic mutations between monozygotic twins with discordant psychiatric disease

Monozygotic (MZ) twins have been thought to be genetically identical. However, recent studies have shown discordant variants between them. We performed whole-exome sequencing (WES) in five MZ twin pairs with discordant neurodevelopmental disorders and one healthy control MZ twin to detect discordant...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hum Genome Var
Egile Nagusiak: Morimoto, Yoshiro, Ono, Shinji, Imamura, Akira, Okazaki, Yuji, Kinoshita, Akira, Mishima, Hiroyuki, Nakane, Hideyuki, Ozawa, Hiroki, Yoshiura, Koh-ichiro, Kurotaki, Naohiro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529667/
https://ncbi.nlm.nih.gov/pubmed/28765789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hgv.2017.32
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