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Deep sequencing reveals variations in somatic cell mosaic mutations between monozygotic twins with discordant psychiatric disease

Monozygotic (MZ) twins have been thought to be genetically identical. However, recent studies have shown discordant variants between them. We performed whole-exome sequencing (WES) in five MZ twin pairs with discordant neurodevelopmental disorders and one healthy control MZ twin to detect discordant...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Hum Genome Var
मुख्य लेखकों: Morimoto, Yoshiro, Ono, Shinji, Imamura, Akira, Okazaki, Yuji, Kinoshita, Akira, Mishima, Hiroyuki, Nakane, Hideyuki, Ozawa, Hiroki, Yoshiura, Koh-ichiro, Kurotaki, Naohiro
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529667/
https://ncbi.nlm.nih.gov/pubmed/28765789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hgv.2017.32
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