Загрузка...
The initial substrate-binding site of γ-secretase is located on presenilin near the active site
γ-Secretase is a structurally enigmatic multiprotein complex that catalyzes intramembrane proteolysis of a variety of substrates, including the amyloid β-protein precursor of Alzheimer's disease and the Notch receptor essential to cell differentiation. The active site of this transmembrane aspa...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2005
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC552920/ https://ncbi.nlm.nih.gov/pubmed/15722417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407640102 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|