Evidence that down-regulation of beta-cell glucose transporters in non-insulin-dependent diabetes may be the cause of diabetic hyperglycemia.

Non-insulin-dependent diabetes mellitus (NIDDM) is attributed to a failure of pancreatic beta cells to maintain insulin secretion at a level sufficient to compensate for underlying insulin resistance. In the ZDF rat, a model of NIDDM that closely resembles the human syndrome, we have previously repo...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Orci, L, Ravazzola, M, Baetens, D, Inman, L, Amherdt, M, Peterson, R G, Newgard, C B, Johnson, J H, Unger, R H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55292/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2263645/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9953
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