Evidence that down-regulation of beta-cell glucose transporters in non-insulin-dependent diabetes may be the cause of diabetic hyperglycemia.

Non-insulin-dependent diabetes mellitus (NIDDM) is attributed to a failure of pancreatic beta cells to maintain insulin secretion at a level sufficient to compensate for underlying insulin resistance. In the ZDF rat, a model of NIDDM that closely resembles the human syndrome, we have previously repo...

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Bibliografiske detaljer
Main Authors: Orci, L, Ravazzola, M, Baetens, D, Inman, L, Amherdt, M, Peterson, R G, Newgard, C B, Johnson, J H, Unger, R H
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55292/
https://ncbi.nlm.nih.gov/pubmed/2263645
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