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Probing site-specific conformational distributions in protein folding with solid-state NMR
We demonstrate an experimental approach to structural studies of unfolded and partially folded proteins in which conformational distributions are probed at a site-specific level by 2D solid-state (13)C NMR spectroscopy of glassy frozen solutions. Experiments on chemical denaturation of the 35-residu...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15718283/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0406130102 |
| Oznake: |
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