Quantitative Determination of Site-Specific Conformational Distributions in an Unfolded Protein by Solid State Nuclear Magnetic Resonance

Solid state nuclear magnetic resonance (NMR) techniques are used to investigate the structure of the 35-residue villin headpiece subdomain (HP35) in folded, partially denatured, and fully denatured states. Experiments are carried out in frozen glycerol/water solutions, with chemical denaturation by...

Full description

Saved in:
Bibliographic Details
Main Authors: Hu, Kan-Nian, Havlin, Robert H., Yau, Wai-Ming, Tycko, Robert
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754388/
https://ncbi.nlm.nih.gov/pubmed/19647001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.073
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items