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mTORC1 and DNA‐PKcs as novel molecular determinants of sensitivity to Chk1 inhibition
Background:Chk1 inhibitors are currently under clinical evaluation as single agents and in combination with cytotoxic chemotherapy. Understanding determinants of sensitivity and novel combinations is critical for further clinical development. Potentiation of mTOR inhibitor cytotoxicity by the Chk1 i...
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| Publicado no: | Mol Oncol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528927/ https://ncbi.nlm.nih.gov/pubmed/26471831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.08.004 |
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