Robust BRCA1‐like classification of copy number profiles of samples repeated across different datasets and platforms

Breast cancers with BRCA1 germline mutation have a characteristic DNA copy number (CN) pattern. We developed a test that assigns CN profiles to be ‘BRCA1‐like’ or ‘non‐BRCA1‐like’, which refers to resembling a BRCA1‐mutated tumor or resembling a tumor without a BRCA1 mutation, respectively. Approxim...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Schouten, Philip C., Grigoriadis, Anita, Kuilman, Thomas, Mirza, Hasan, Watkins, Johnathan A., Cooke, Saskia A., van Dyk, Ewald, Severson, Tesa M., Rueda, Oscar M., Hoogstraat, Marlous, Verhagen, Caroline V.M., Natrajan, Rachael, Chin, Suet-Feung, Lips, Esther H., Kruizinga, Janneke, Velds, Arno, Nieuwland, Marja, Kerkhoven, Ron M., Krijgsman, Oscar, Vens, Conchita, Peeper, Daniel, Nederlof, Petra M., Caldas, Carlos, Tutt, Andrew N., Wessels, Lodewyk F., Linn, Sabine C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528812/
https://ncbi.nlm.nih.gov/pubmed/25825120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.03.002
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