BRCA1 regulates transforming growth factor‐β (TGF‐β1) signaling through Gadd45a by enhancing the protein stability of Smad4

BRCA1 is a well established tumor suppressor gene, which is involved in many cellular processes, including DNA damage repair, cell cycle control, apoptosis, as well as transcriptional control. In this work, we have found that BRCA1 is involved in regulating TGF‐β1/Smad pathway. The loss of endogenou...

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Vydáno v:Mol Oncol
Hlavní autoři: Li, Dan, Kang, Nan, Ji, Junfang, Zhan, Qimin
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528796/
https://ncbi.nlm.nih.gov/pubmed/26022109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.05.002
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