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BRCA1 regulates transforming growth factor‐β (TGF‐β1) signaling through Gadd45a by enhancing the protein stability of Smad4
BRCA1 is a well established tumor suppressor gene, which is involved in many cellular processes, including DNA damage repair, cell cycle control, apoptosis, as well as transcriptional control. In this work, we have found that BRCA1 is involved in regulating TGF‐β1/Smad pathway. The loss of endogenou...
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| Publicado no: | Mol Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528796/ https://ncbi.nlm.nih.gov/pubmed/26022109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.05.002 |
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