Significance of TP53 mutations as predictive markers of adjuvant cisplatin‐based chemotherapy in completely resected non‐small‐cell lung cancer

Adjuvant cisplatin‐based chemotherapy only marginally improves survival in patients with completely resected non‐small‐cell lung cancer (NSCLC). We have evaluated the predictive value of mutations in TP53, encoding the tumour suppressor p53, in the International Adjuvant Lung Cancer Trial (IALT), a...

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Bibliografiske detaljer
Udgivet i:Mol Oncol
Main Authors: Ma, Xiaoli, Rousseau, Vanessa, Sun, Haiji, Lantuejoul, Sylvie, Filipits, Martin, Pirker, Robert, Popper, Helmut, Mendiboure, Jean, Vataire, Anne-Lise, Le Chevalier, Thierry, Soria, Jean Charles, Brambilla, Elisabeth, Dunant, Ariane, Hainaut, Pierre
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2014
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528648/
https://ncbi.nlm.nih.gov/pubmed/24495481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.12.015
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