Significance of TP53 mutations as predictive markers of adjuvant cisplatin‐based chemotherapy in completely resected non‐small‐cell lung cancer

Adjuvant cisplatin‐based chemotherapy only marginally improves survival in patients with completely resected non‐small‐cell lung cancer (NSCLC). We have evaluated the predictive value of mutations in TP53, encoding the tumour suppressor p53, in the International Adjuvant Lung Cancer Trial (IALT), a...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Ma, Xiaoli, Rousseau, Vanessa, Sun, Haiji, Lantuejoul, Sylvie, Filipits, Martin, Pirker, Robert, Popper, Helmut, Mendiboure, Jean, Vataire, Anne-Lise, Le Chevalier, Thierry, Soria, Jean Charles, Brambilla, Elisabeth, Dunant, Ariane, Hainaut, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528648/
https://ncbi.nlm.nih.gov/pubmed/24495481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.12.015
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