Preclinical study on combined chemo‐ and nonviral gene therapy for sensitization of melanoma using a human TNF‐alpha expressing MIDGE DNA vector

Nonviral gene therapy represents a realistic option for clinical application in cancer treatment. This preclinical study demonstrates the advantage of using the small‐size MIDGE® DNA vector for improved transgene expression and therapeutic application. This is caused by significant increase in trans...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Kobelt, Dennis, Aumann, Jutta, Schmidt, Manuel, Wittig, Burghardt, Fichtner, Iduna, Behrens, Diana, Lemm, Margit, Freundt, Greta, Schlag, Peter M., Walther, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528640/
https://ncbi.nlm.nih.gov/pubmed/24503218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.12.019
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