Peripheral non-viral MIDGE vector-driven delivery of β-endorphin in inflammatory pain

BACKGROUND: Leukocytes infiltrating inflamed tissue produce and release opioid peptides such as β-endorphin, which activate opioid receptors on peripheral terminals of sensory nerves resulting in analgesia. Gene therapy is an attractive strategy to enhance continuous production of endogenous opioids...

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Detalhes bibliográficos
Main Authors: Machelska, Halina, Schroff, Matthias, Oswald, Detlef, Binder, Waltraud, Sitte, Nicolle, Mousa, Shaaban A, Rittner, Heike L, Brack, Alexander, Labuz, Dominika, Busch, Melanie, Wittig, Burghardt, Schäfer, Michael, Stein, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797781/
https://ncbi.nlm.nih.gov/pubmed/20003437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-5-72
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