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Intervening in β-Catenin Signaling by Sulindac Inhibits S100A4-Dependent Colon Cancer Metastasis

Colon cancer metastasis is often associated with activation of the Wnt/β-catenin signaling pathway and high expression of the metastasis mediator S100A4. We previously demonstrated the transcriptional regulation of S100A4 by β-catenin and the importance of the interconnection of these cellular progr...

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Autors principals: Stein, Ulrike, Arlt, Franziska, Smith, Janice, Sack, Ulrike, Herrmann, Pia, Walther, Wolfgang, Lemm, Margit, Fichtner, Iduna, Shoemaker, Robert H, Schlag, Peter M
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033592/
https://ncbi.nlm.nih.gov/pubmed/21403839
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