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TP53 mutation‐correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53‐mutated breast cancers

Breast cancers (BC) carry a complex set of gene mutations that can influence their gene expression and clinical behavior. We aimed to identify genes driven by the TP53 mutation status and assess their clinical relevance in estrogen receptor (ER)‐positive and ER‐negative BC, and their potential as ta...

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Publicado en:Mol Oncol
Autores principales: Győrffy, Balázs, Bottai, Giulia, Lehmann-Che, Jacqueline, Kéri, György, Őrfi, László, Iwamoto, Takayuki, Desmedt, Christine, Bianchini, Giampaolo, Turner, Nicholas C., de Thè, Hugues, André, Fabrice, Sotiriou, Christos, Hortobagyi, Gabriel N., Di Leo, Angelo, Pusztai, Lajos, Santarpia, Libero
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528634/
https://ncbi.nlm.nih.gov/pubmed/24462521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.12.018
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