TP53 mutation‐correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53‐mutated breast cancers

Breast cancers (BC) carry a complex set of gene mutations that can influence their gene expression and clinical behavior. We aimed to identify genes driven by the TP53 mutation status and assess their clinical relevance in estrogen receptor (ER)‐positive and ER‐negative BC, and their potential as ta...

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Veröffentlicht in:Mol Oncol
Hauptverfasser: Győrffy, Balázs, Bottai, Giulia, Lehmann-Che, Jacqueline, Kéri, György, Őrfi, László, Iwamoto, Takayuki, Desmedt, Christine, Bianchini, Giampaolo, Turner, Nicholas C., de Thè, Hugues, André, Fabrice, Sotiriou, Christos, Hortobagyi, Gabriel N., Di Leo, Angelo, Pusztai, Lajos, Santarpia, Libero
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2014
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528634/
https://ncbi.nlm.nih.gov/pubmed/24462521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.12.018
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