TP53 mutation‐correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53‐mutated breast cancers

Breast cancers (BC) carry a complex set of gene mutations that can influence their gene expression and clinical behavior. We aimed to identify genes driven by the TP53 mutation status and assess their clinical relevance in estrogen receptor (ER)‐positive and ER‐negative BC, and their potential as ta...

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Publicado no:Mol Oncol
Main Authors: Győrffy, Balázs, Bottai, Giulia, Lehmann-Che, Jacqueline, Kéri, György, Őrfi, László, Iwamoto, Takayuki, Desmedt, Christine, Bianchini, Giampaolo, Turner, Nicholas C., de Thè, Hugues, André, Fabrice, Sotiriou, Christos, Hortobagyi, Gabriel N., Di Leo, Angelo, Pusztai, Lajos, Santarpia, Libero
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528634/
https://ncbi.nlm.nih.gov/pubmed/24462521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.12.018
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