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Sequential Cdk1 and Plk1 phosphorylation of caspase‐8 triggers apoptotic cell death during mitosis
Caspase‐8 is crucial for cell death induction, especially via the death receptor pathway. The dysregulated expression or function of caspase‐8 can promote tumor formation, progression and treatment resistance in different human cancers. Here, we show procaspase‐8 is regulated during the cell cycle t...
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| Publicat a: | Mol Oncol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528627/ https://ncbi.nlm.nih.gov/pubmed/24484936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.12.013 |
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