Inhibition of PARP1‐dependent end‐joining contributes to Olaparib‐mediated radiosensitization in tumor cells

Poly‐ADP‐ribose‐polymerase inhibitors (PARPi) are considered to be optimal tools for specifically enhancing radiosensitivity. This effect has been shown to be replication‐dependent and more profound in HR‐deficient tumors. Here, we present a new mode of PARPi‐mediated radiosensitization which was ob...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Mol Oncol
Glavni autori: Kötter, Annika, Cornils, Kerstin, Borgmann, Kerstin, Dahm-Daphi, Jochen, Petersen, Cordula, Dikomey, Ekkehard, Mansour, Wael Y.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2014
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528607/
https://ncbi.nlm.nih.gov/pubmed/25028150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.008
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items