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Pharmacologic inhibition of vacuolar H+ ATPase reduces physiologic and oncogenic Notch signaling
Notch signaling in prominently involved in growth regulation in metazoan tissues. Because of this, Notch is often upregulated in cancer and current efforts point to developing drugs that block its activation. Notch receptor endocytosis towards acidic compartments is a recently appreciated determinan...
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| 出版年: | Mol Oncol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528540/ https://ncbi.nlm.nih.gov/pubmed/24309677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.11.002 |
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