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Mode of Cell Death Induction by Pharmacological Vacuolar H(+)-ATPase (V-ATPase) Inhibition

The vacuolar H(+)-ATPase (V-ATPase), a multisubunit proton pump, has come into focus as an attractive target in cancer invasion. However, little is known about the role of V-ATPase in cell death, and especially the underlying mechanisms remain mostly unknown. We used the myxobacterial macrolide arch...

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Bibliografiska uppgifter
Huvudupphovsmän: von Schwarzenberg, Karin, Wiedmann, Romina M., Oak, Prajakta, Schulz, Sabine, Zischka, Hans, Wanner, Gerhard, Efferth, Thomas, Trauner, Dirk, Vollmar, Angelika M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543021/
https://ncbi.nlm.nih.gov/pubmed/23168408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412007
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