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14‐3‐3 and β‐catenin are secreted on extracellular vesicles to activate the oncogenic Wnt pathway
Aberrant activation of the canonical Wnt signal transduction pathway is involved in a large number of human diseases. β‐catenin, the key effector protein of the canonical Wnt pathway, functions in the nucleus with T‐cell factor/lymphoid enhancer factor (TCF/LEF) to activate expression of Wnt target...
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| Veröffentlicht in: | Mol Oncol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528515/ https://ncbi.nlm.nih.gov/pubmed/24721736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.03.011 |
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