14‐3‐3 and β‐catenin are secreted on extracellular vesicles to activate the oncogenic Wnt pathway

Aberrant activation of the canonical Wnt signal transduction pathway is involved in a large number of human diseases. β‐catenin, the key effector protein of the canonical Wnt pathway, functions in the nucleus with T‐cell factor/lymphoid enhancer factor (TCF/LEF) to activate expression of Wnt target...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Dovrat, Shiri, Caspi, Michal, Zilberberg, Alona, Lahav, Lital, Firsow, Anastasia, Gur, Hila, Rosin-Arbesfeld, Rina
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2014
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528515/
https://ncbi.nlm.nih.gov/pubmed/24721736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.03.011
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