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A Novel Functional Screen in Human Cells Identifies MOCA as a Negative Regulator of Wnt Signaling

Aberrant Wnt signal transduction is involved in many human diseases such as cancer and neurodegenerative disorders. The key effector protein of the canonical Wnt pathway is β-catenin, which functions with T-cell factor/lymphoid enhancer factor (TCF/LEF) to activate gene transcription that leads to e...

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Autors principals: Caspi, Elanite, Rosin-Arbesfeld, Rina
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575172/
https://ncbi.nlm.nih.gov/pubmed/18716063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-10-1046
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