Canonical Wnt signaling negatively regulates platelet function

Wnts regulate important intracellular signaling events, and dysregulation of the Wnt pathway has been linked to human disease. Here, we uncover numerous Wnt canonical effectors in human platelets where Wnts, their receptors, and downstream signaling components have not been previously described. We...

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Bibliographische Detailangaben
Hauptverfasser: Steele, Brian M., Harper, Matthew T., Macaulay, Iain C., Morrell, Craig N., Perez-Tamayo, Alita, Foy, Martina, Habas, Raymond, Poole, Alastair W., Fitzgerald, Desmond J., Maguire, Patricia B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785253/
https://ncbi.nlm.nih.gov/pubmed/19901330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906268106
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