High‐throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth

MicroRNAs (miRNAs) are non‐coding RNAs regulating gene expression post‐transcriptionally. We have characterized the role of miRNAs in regulating the human epidermal growth factor receptor 2 (HER2)‐pathway in breast cancer. We performed miRNA gain‐of‐function assays by screening two HER2 amplified ce...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Leivonen, Suvi-Katri, Sahlberg, Kristine Kleivi, Mäkelä, Rami, Due, Eldri Undlien, Kallioniemi, Olli, Børresen-Dale, Anne-Lise, Perälä, Merja
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2013
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528509/
https://ncbi.nlm.nih.gov/pubmed/24148764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.10.001
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