High‐throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth

MicroRNAs (miRNAs) are non‐coding RNAs regulating gene expression post‐transcriptionally. We have characterized the role of miRNAs in regulating the human epidermal growth factor receptor 2 (HER2)‐pathway in breast cancer. We performed miRNA gain‐of‐function assays by screening two HER2 amplified ce...

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Detalles Bibliográficos
Publicado en:Mol Oncol
Main Authors: Leivonen, Suvi-Katri, Sahlberg, Kristine Kleivi, Mäkelä, Rami, Due, Eldri Undlien, Kallioniemi, Olli, Børresen-Dale, Anne-Lise, Perälä, Merja
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2013
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528509/
https://ncbi.nlm.nih.gov/pubmed/24148764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.10.001
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