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High‐throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth

MicroRNAs (miRNAs) are non‐coding RNAs regulating gene expression post‐transcriptionally. We have characterized the role of miRNAs in regulating the human epidermal growth factor receptor 2 (HER2)‐pathway in breast cancer. We performed miRNA gain‐of‐function assays by screening two HER2 amplified ce...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Leivonen, Suvi-Katri, Sahlberg, Kristine Kleivi, Mäkelä, Rami, Due, Eldri Undlien, Kallioniemi, Olli, Børresen-Dale, Anne-Lise, Perälä, Merja
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528509/
https://ncbi.nlm.nih.gov/pubmed/24148764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.10.001
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