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High‐throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth

MicroRNAs (miRNAs) are non‐coding RNAs regulating gene expression post‐transcriptionally. We have characterized the role of miRNAs in regulating the human epidermal growth factor receptor 2 (HER2)‐pathway in breast cancer. We performed miRNA gain‐of‐function assays by screening two HER2 amplified ce...

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Bibliografiske detaljer
Udgivet i:Mol Oncol
Main Authors: Leivonen, Suvi-Katri, Sahlberg, Kristine Kleivi, Mäkelä, Rami, Due, Eldri Undlien, Kallioniemi, Olli, Børresen-Dale, Anne-Lise, Perälä, Merja
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528509/
https://ncbi.nlm.nih.gov/pubmed/24148764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.10.001
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