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Identification of MicroRNAs Inhibiting TGF-β-Induced IL-11 Production in Bone Metastatic Breast Cancer Cells

Development of bone metastases is dependent on the cancer cell-bone cell interactions in the bone microenvironment. Transforming growth factor β (TGF-β) is released from bone during osteoclastic bone resorption and induces production of osteolytic factors, such as interleukin 11 (IL-11), in breast c...

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Detalhes bibliográficos
Main Authors: Pollari, Sirkku, Leivonen, Suvi-Katri, Perälä, Merja, Fey, Vidal, Käkönen, Sanna-Maria, Kallioniemi, Olli
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357420/
https://ncbi.nlm.nih.gov/pubmed/22629385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037361
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