Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1

TRAP1 is a mitochondrial antiapoptotic protein up‐regulated in several human malignancies. However, recent evidences suggest that TRAP1 is also localized in the endoplasmic reticulum (ER) where it is involved in ER stress protection and protein quality control of tumor cells. Based on the mechanisti...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Maddalena, Francesca, Sisinni, Lorenza, Lettini, Giacomo, Condelli, Valentina, Matassa, Danilo Swann, Piscazzi, Annamaria, Amoroso, Maria Rosaria, La Torre, Giuseppe, Esposito, Franca, Landriscina, Matteo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2013
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528458/
https://ncbi.nlm.nih.gov/pubmed/23735188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.04.009
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