Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1

TRAP1 is a mitochondrial antiapoptotic protein up‐regulated in several human malignancies. However, recent evidences suggest that TRAP1 is also localized in the endoplasmic reticulum (ER) where it is involved in ER stress protection and protein quality control of tumor cells. Based on the mechanisti...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Maddalena, Francesca, Sisinni, Lorenza, Lettini, Giacomo, Condelli, Valentina, Matassa, Danilo Swann, Piscazzi, Annamaria, Amoroso, Maria Rosaria, La Torre, Giuseppe, Esposito, Franca, Landriscina, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528458/
https://ncbi.nlm.nih.gov/pubmed/23735188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.04.009
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