Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1

TRAP1 is a mitochondrial antiapoptotic protein up‐regulated in several human malignancies. However, recent evidences suggest that TRAP1 is also localized in the endoplasmic reticulum (ER) where it is involved in ER stress protection and protein quality control of tumor cells. Based on the mechanisti...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Oncol
Auteurs principaux: Maddalena, Francesca, Sisinni, Lorenza, Lettini, Giacomo, Condelli, Valentina, Matassa, Danilo Swann, Piscazzi, Annamaria, Amoroso, Maria Rosaria, La Torre, Giuseppe, Esposito, Franca, Landriscina, Matteo
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2013
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528458/
https://ncbi.nlm.nih.gov/pubmed/23735188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.04.009
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