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Genetic and clinical characterization of 45 acute leukemia patients with MLL gene rearrangements from a single institution

Chromosomal rearrangements affecting the MLL gene are associated with high‐risk pediatric, adult and therapy‐associated acute leukemia. In this study, conventional cytogenetic, fluorescence in situ hybridization, and molecular genetic studies were used to characterize the type and frequency of MLL r...

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Bibliografske podrobnosti
izdano v:Mol Oncol
Main Authors: Cerveira, Nuno, Lisboa, Susana, Correia, Cecília, Bizarro, Susana, Santos, Joana, Torres, Lurdes, Vieira, Joana, Barros-Silva, João D., Pereira, Dulcineia, Moreira, Cláudia, Meyer, Claus, Oliva, Tereza, Moreira, Ilídia, Martins, Ângelo, Viterbo, Luísa, Costa, Vítor, Marschalek, Rolf, Pinto, Armando, Mariz, José M., Teixeira, Manuel R.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528393/
https://ncbi.nlm.nih.gov/pubmed/22846743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.06.004
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