Genetic and clinical characterization of 45 acute leukemia patients with MLL gene rearrangements from a single institution

Chromosomal rearrangements affecting the MLL gene are associated with high‐risk pediatric, adult and therapy‐associated acute leukemia. In this study, conventional cytogenetic, fluorescence in situ hybridization, and molecular genetic studies were used to characterize the type and frequency of MLL r...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Cerveira, Nuno, Lisboa, Susana, Correia, Cecília, Bizarro, Susana, Santos, Joana, Torres, Lurdes, Vieira, Joana, Barros-Silva, João D., Pereira, Dulcineia, Moreira, Cláudia, Meyer, Claus, Oliva, Tereza, Moreira, Ilídia, Martins, Ângelo, Viterbo, Luísa, Costa, Vítor, Marschalek, Rolf, Pinto, Armando, Mariz, José M., Teixeira, Manuel R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2012
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Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528393/
https://ncbi.nlm.nih.gov/pubmed/22846743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.06.004
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