Both SEPT2 and MLL are down-regulated in MLL-SEPT2 therapy-related myeloid neoplasia

BACKGROUND: A relevant role of septins in leukemogenesis has been uncovered by their involvement as fusion partners in MLL-related leukemia. Recently, we have established the MLL-SEPT2 gene fusion as the molecular abnormality subjacent to the translocation t(2;11)(q37;q23) in therapy-related acute m...

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Hauptverfasser: Cerveira, Nuno, Santos, Joana, Bizarro, Susana, Costa, Vera, Ribeiro, Franclim R, Lisboa, Susana, Correia, Cecília, Torres, Lurdes, Vieira, Joana, Snijder, Simone, Mariz, José M, Norton, Lucília, Mellink, Clemens H, Buijs, Arjan, Teixeira, Manuel R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689242/
https://ncbi.nlm.nih.gov/pubmed/19445675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-147
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