Reversal of gastrointestinal carcinoma‐induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL‐12

Immunotherapy‐based strategies for gastrointestinal carcinomas (GIC) have been exploited so far, but these approaches have to face strong mechanisms of immune escape induced by tumours. We previously demonstrated that sub‐therapeutic doses of an adenovirus expressing IL‐12 genes (AdIL‐12) mediated a...

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Bibliografiset tiedot
Julkaisussa:Mol Oncol
Päätekijät: Malvicini, Mariana, Ingolotti, Mariana, Piccioni, Flavia, Garcia, Mariana, Bayo, Juan, Atorrasagasti, Catalina, Alaniz, Laura, Aquino, Jorge B., Espinoza, Jaime A., Gidekel, Manuel, Scharovsky, O. Graciela, Matar, Pablo, Mazzolini, Guillermo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2011
Aiheet:
Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528288/
https://ncbi.nlm.nih.gov/pubmed/21515097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.03.007
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