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Reversal of gastrointestinal carcinoma‐induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL‐12

Immunotherapy‐based strategies for gastrointestinal carcinomas (GIC) have been exploited so far, but these approaches have to face strong mechanisms of immune escape induced by tumours. We previously demonstrated that sub‐therapeutic doses of an adenovirus expressing IL‐12 genes (AdIL‐12) mediated a...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Mol Oncol
Κύριοι συγγραφείς: Malvicini, Mariana, Ingolotti, Mariana, Piccioni, Flavia, Garcia, Mariana, Bayo, Juan, Atorrasagasti, Catalina, Alaniz, Laura, Aquino, Jorge B., Espinoza, Jaime A., Gidekel, Manuel, Scharovsky, O. Graciela, Matar, Pablo, Mazzolini, Guillermo
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley and Sons Inc. 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528288/
https://ncbi.nlm.nih.gov/pubmed/21515097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.03.007
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