DNA methylation patterns in luminal breast cancers differ from non‐luminal subtypes and can identify relapse risk independent of other clinical variables

The diversity of breast cancers reflects variations in underlying biology and affects the clinical implications for patients. Gene expression studies have identified five major subtypes– Luminal A, Luminal B, basal‐like, ErbB2+ and Normal‐Like. We set out to determine the role of DNA methylation in...

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Gepubliceerd in:Mol Oncol
Hoofdauteurs: Kamalakaran, Sitharthan, Varadan, Vinay, Giercksky Russnes, Hege E., Levy, Dan, Kendall, Jude, Janevski, Angel, Riggs, Michael, Banerjee, Nilanjana, Synnestvedt, Marit, Schlichting, Ellen, Kåresen, Rolf, Shama Prasada, K., Rotti, Harish, Rao, Ramachandra, Rao, Laxmi, Eric Tang, Man-Hung, Satyamoorthy, K., Lucito, Robert, Wigler, Michael, Dimitrova, Nevenka, Naume, Bjorn, Borresen-Dale, Anne-Lise, Hicks, James B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528275/
https://ncbi.nlm.nih.gov/pubmed/21169070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2010.11.002
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