Particulate array of well-ordered HIV clade C Env trimers elicits neutralizing antibodies that display a unique V2 cap approach

The development of soluble envelope glycoprotein (Env) mimetics displaying ordered trimeric symmetry has ushered in a new era in HIV-1 vaccination. The recently reported native, flexibly linked (NFL) design allows the generation of native-like trimers from clinical isolates at high yields and homoge...

詳細記述

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書誌詳細
出版年:Immunity
主要な著者: Martinez-Murillo, Paola, Tran, Karen, Guenaga, Javier, Lindgren, Gustaf, Àdori, Monika, Feng, Yu, Phad, Ganesh E., Bernat, Néstor Vázquez, Bale, Shridhar, Ingale, Jidnyasa, Dubrovskaya, Viktoriya, O’Dell, Sijy, Pramanik, Lotta, Spångberg, Mats, Corcoran, Martin, Loré, Karin, Mascola, John R., Wyatt, Richard T., Karlsson Hedestam, Gunilla B.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528178/
https://ncbi.nlm.nih.gov/pubmed/28514687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.04.021
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