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Sphingosine 1-phosphate lyase enhances the activation of IKKε to promote type I interferon-mediated innate immune response to influenza A virus infection
Sphingosine 1-phosphate (S1P) lyase (SPL) is an intracellular enzyme that mediates the irreversible degradation of the bioactive lipid, S1P. We have previously reported that overexpressed SPL displays anti-influenza viral activity; however the underlying mechanism is incompletely understood. In this...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528153/ https://ncbi.nlm.nih.gov/pubmed/28600291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601959 |
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