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Intramolecular Hydrogen Atom Transfer in Aminyl Radical at Room Temperature with Large Kinetic Isotope Effect

We report a large kinetic isotope effect at 298 K, k(H)/k(D) ≈ 150, associated with an intramolecular 1,5-hydrogen atom transfer (1,5-HAT) in the decay of PEGylated carbazyl (aminyl) radical in solution. The experimental observations surprisingly combine the hallmarks of tunneling, including large K...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Wang, Ying, Olankitwanit, Arnon, Rajca, Suchada, Rajca, Andrzej
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528148/
https://ncbi.nlm.nih.gov/pubmed/28514849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b02692
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