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Aberrations of the MRE11–RAD50–NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer‐predisposing gene
The MRE11, RAD50, and NBS1 genes encode proteins of the MRE11–RAD50–NBS1 (MRN) complex critical for proper maintenance of genomic integrity and tumour suppression; however, the extent and impact of their cancer‐predisposing defects, and potential clinical value remain to be determined. Here, we repo...
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| Pubblicato in: | Mol Oncol |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5527773/ https://ncbi.nlm.nih.gov/pubmed/19383352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2008.09.007 |
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