Selective Killing of Dormant Mycobacterium tuberculosis by Marine Natural Products

The dormant phenotype acquired by Mycobacterium tuberculosis during infection poses a major challenge in disease treatment, since these bacilli show tolerance to front-line drugs. Therefore, it is imperative to find novel compounds that effectively kill dormant bacteria. By screening 4,400 marine na...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Rodrigues Felix, Carolina, Gupta, Rashmi, Geden, Sandra, Roberts, Jill, Winder, Priscilla, Pomponi, Shirley A., Diaz, Maria Cristina, Reed, John K., Wright, Amy E., Rohde, Kyle H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527660/
https://ncbi.nlm.nih.gov/pubmed/28607021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00743-17
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