Delamanid Kills Dormant Mycobacteria In Vitro and in a Guinea Pig Model of Tuberculosis

Tuberculosis (TB) treatment is long and requires multiple drugs, likely due to various phenotypes of TB bacilli with variable drug susceptibilities. Drugs with broad activity are urgently needed. This study aimed to evaluate delamanid's activity against growing or dormant bacilli in vitro as we...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Chen, Xiuhao, Hashizume, Hiroyuki, Tomishige, Tatsuo, Nakamura, Izuru, Matsuba, Miki, Fujiwara, Mamoru, Kitamoto, Ryuki, Hanaki, Erina, Ohba, Yoshio, Matsumoto, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444171/
https://ncbi.nlm.nih.gov/pubmed/28373190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02402-16
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