Delamanid Kills Dormant Mycobacteria In Vitro and in a Guinea Pig Model of Tuberculosis

Tuberculosis (TB) treatment is long and requires multiple drugs, likely due to various phenotypes of TB bacilli with variable drug susceptibilities. Drugs with broad activity are urgently needed. This study aimed to evaluate delamanid's activity against growing or dormant bacilli in vitro as we...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Chen, Xiuhao, Hashizume, Hiroyuki, Tomishige, Tatsuo, Nakamura, Izuru, Matsuba, Miki, Fujiwara, Mamoru, Kitamoto, Ryuki, Hanaki, Erina, Ohba, Yoshio, Matsumoto, Makoto
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444171/
https://ncbi.nlm.nih.gov/pubmed/28373190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02402-16
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