NMR metabolomics highlights sphingosine kinase‐1 as a new molecular switch in the orchestration of aberrant metabolic phenotype in cancer cells

Strong experimental evidence in animal and cellular models supports a pivotal role of sphingosine kinase‐1 (SK1) in oncogenesis. In many human cancers, SK1 levels are upregulated and these increases are linked to poor prognosis in patients. Here, by employing untargeted NMR‐based metabolomic profili...

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Detaylı Bibliyografya
Yayımlandı:Mol Oncol
Asıl Yazarlar: Bernacchioni, Caterina, Ghini, Veronica, Cencetti, Francesca, Japtok, Lukasz, Donati, Chiara, Bruni, Paola, Turano, Paola
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527469/
https://ncbi.nlm.nih.gov/pubmed/28258651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12048
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