Dysregulation of the miR‐194–CUL4B negative feedback loop drives tumorigenesis in non‐small‐cell lung carcinoma

Cullin 4B (CUL4B), a scaffold protein that assembles CRL4B ubiquitin ligase complexes, is overexpressed in many types of cancers and represses many tumor suppressors through epigenetic mechanisms. However, the mechanisms by which CUL4B is upregulated remain to be elucidated. Here, we show that CUL4B...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Oncol
मुख्य लेखकों: Mi, Jun, Zou, Yongxin, Lin, Xiaohua, Lu, Juanjuan, liu, Xiaochen, Zhao, Hui, Ye, Xiang, Hu, Huili, Jiang, Baichun, Han, Bo, Shao, Changshun, Gong, Yaoqin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2017
विषय:
Research Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527444/
https://ncbi.nlm.nih.gov/pubmed/28164432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12038
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन