BRG1-SWI/SNF-dependent regulation of the Wt1 transcriptional landscape mediates epicardial activity during heart development and disease

Epicardium-derived cells (EPDCs) contribute cardiovascular cell types during development and in adulthood respond to Thymosin β4 (Tβ4) and myocardial infarction (MI) by reactivating a fetal gene programme to promote neovascularization and cardiomyogenesis. The mechanism for epicardial gene (re-)acti...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Vieira, Joaquim Miguel, Howard, Sara, Villa del Campo, Cristina, Bollini, Sveva, Dubé, Karina N., Masters, Megan, Barnette, Damien N., Rohling, Mala, Sun, Xin, Hankins, Laura E., Gavriouchkina, Daria, Williams, Ruth, Metzger, Daniel, Chambon, Pierre, Sauka-Spengler, Tatjana, Davies, Benjamin, Riley, Paul R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527284/
https://ncbi.nlm.nih.gov/pubmed/28737171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms16034
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