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Klotho/FGF23 Axis in Chronic Kidney Disease and Cardiovascular Disease

BACKGROUND: Membrane αKlotho (hereinafter called Klotho) is highly expressed in the kidney and functions as a coreceptor of FGF receptors (FGFRs) to activate specific fibroblast growth factor 23 (FGF23) signal pathway. FGF23 is produced in bones and participates in the maintenance of mineral homeost...

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書目詳細資料
發表在:Kidney Dis (Basel)
Main Authors: Lu, Xiang, Hu, Ming Chang
格式: Artigo
語言:Inglês
出版: S. Karger AG 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527179/
https://ncbi.nlm.nih.gov/pubmed/28785560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000452880
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