Thy-1(+) Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis

Cancer-associated fibroblasts (CAFs) regulate diverse intratumoral biological programs and can promote or inhibit tumorigenesis, but those CAF populations that negatively impact the clinical outcome of lung cancer patients have not been fully elucidated. Because Thy-1 (CD90) marks CAFs that promote...

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Publicado no:Sci Rep
Main Authors: Schliekelman, Mark J., Creighton, Chad J., Baird, Brandi N., Chen, Yulong, Banerjee, Priyam, Bota-Rabassedas, Neus, Ahn, Young-Ho, Roybal, Jonathon D., Chen, Fengju, Zhang, Yiqun, Mishra, Dhruva K., Kim, Min P., Liu, Xin, Mino, Barbara, Villalobos, Pamela, Rodriguez-Canales, Jaime, Behrens, Carmen, Wistuba, Ignacio I., Hanash, Samir M., Kurie, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527099/
https://ncbi.nlm.nih.gov/pubmed/28744021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06922-5
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